KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS6
All Species:
29.39
Human Site:
S251
Identified Species:
53.89
UniProt:
O14544
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14544
NP_004223.2
535
59528
S251
S
S
S
P
M
E
V
S
A
V
P
P
Q
V
G
Chimpanzee
Pan troglodytes
XP_512211
535
59559
S251
S
S
S
P
M
E
V
S
A
V
P
P
Q
V
G
Rhesus Macaque
Macaca mulatta
XP_001095656
535
59456
S251
S
S
S
P
M
E
V
S
A
V
P
P
P
G
G
Dog
Lupus familis
XP_533377
535
59510
S251
G
S
S
P
M
E
V
S
A
V
P
P
Q
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLY0
533
58875
S249
T
S
S
P
M
E
V
S
A
V
P
L
P
G
A
Rat
Rattus norvegicus
XP_001063512
547
60813
S263
T
S
S
P
M
E
V
S
A
V
P
L
P
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
C241
P
L
E
G
S
R
S
C
C
P
D
G
S
S
P
Chicken
Gallus gallus
NP_001120784
534
59819
S250
S
S
S
P
M
E
V
S
T
V
S
S
Q
V
G
Frog
Xenopus laevis
NP_001086732
533
60367
S250
R
S
S
P
M
E
I
S
T
I
P
S
Q
I
G
Zebra Danio
Brachydanio rerio
XP_687041
519
57925
G242
G
P
S
P
M
E
V
G
D
Q
V
E
S
D
S
Tiger Blowfish
Takifugu rubipres
NP_001116334
531
59124
T250
S
S
P
M
E
V
V
T
E
A
D
D
T
S
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624532
358
41531
S81
Q
N
N
K
S
T
I
S
I
E
E
N
N
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780887
391
44540
L114
A
E
I
F
E
E
R
L
D
E
C
L
E
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
94.5
N.A.
84.3
82.4
N.A.
77.5
90.2
81.6
70.4
72.7
N.A.
30
N.A.
30
Protein Similarity:
100
99.6
98.8
96.4
N.A.
88.7
87.1
N.A.
83.3
95.5
91.4
81.6
83.5
N.A.
46.1
N.A.
45.7
P-Site Identity:
100
100
86.6
93.3
N.A.
66.6
66.6
N.A.
0
80
60
33.3
20
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
86.6
93.3
N.A.
73.3
73.3
N.A.
0
80
80
33.3
26.6
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
47
8
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
16
0
16
8
0
8
8
% D
% Glu:
0
8
8
0
16
77
0
0
8
16
8
8
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
8
0
0
0
8
0
0
0
8
0
24
47
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
16
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
0
24
0
0
8
% L
% Met:
0
0
0
8
70
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
0
0
8
8
8
0
% N
% Pro:
8
8
8
70
0
0
0
0
0
8
54
31
24
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
39
0
0
% Q
% Arg:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% R
% Ser:
39
70
70
0
16
0
8
70
0
0
8
16
16
16
16
% S
% Thr:
16
0
0
0
0
8
0
8
16
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
8
70
0
0
54
8
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _